New vaccine for diarrhea passes safety trials: Study

London,  November 21 :

In the United Kingdom, a research study published in the science journal, The Lancet, on Infectious Diseases said that a potential vaccine against diarrhea has been proved safe and effective in an early-stage clinical trial.

The trial was carried out in Bangladesh.

The study found the safety and effectiveness of an oral, inactivated vaccine candidate – ETVAX – against toxin-producing E- Coli bacteria which caused diarrhea.

According to the researchers, including those from the University of Gothenburg in Sweden, the specific type of the bacteria are the primary cause of diarrhea, leading to substantial illness and death in children in Low and Middle-Income Countries (LMICs) as well as in travellers to LMICs.

They said there is no vaccine available yet for use for either children or travellers to high-risk areas and added that vaccine development for the infectious diarrheal diseases was a World Health Organization (WHO) priority.

The scientists selected 450 infants and children in Bangladesh between six months to five years of age as participants for the study. The study noted that 80-100 per cent of the children between two and five years of age and 50-80 per cent of infants between six and eleven months of age responded to all key immunity generating components of the vaccine.